Patient Data, Genetically-Enriched
Genetic data has an increasingly important role in the discovery and development of precision medicines.
Our unique data access allows Arcturis to develop deep, highly curated phenotypic datasets by enriching electronic health records with genetic data.
Precision data. Precision medicine.
Whole genome sequencing and other techniques are generating vast quantities of genetic information about an individual that can be used to help diagnose disease, predict susceptibility to and progression of disease, and inform about the potential response to treatment.
The advances in sequencing and screening techniques means that genetic information is increasingly playing a role in improving the clinical care of patients. For example, understanding the genetic makeup of individual patients means it is possible for them to be matched to the most effective medical intervention and medications to improve outcomes.
Arcturis is using its data access to link genetic and patient data to support drug discovery and clinical development.
Our Next Generation Sequencing Platform
Our HRA-approved research database enables us to curate deep, disease-specific clinical data from individual NHS hospitals and other research organisations in the UK. Our relationships with NHS hospitals also allows us to access genetic and molecular data including genomics (DNA), transcriptomic (RNA) and proteomic (proteins).
We are then able to take these genetic data, generated through whole genome sequencing, single-cell analysis or other approaches, and link them to the electronic health records to form our Next Generation Sequencing Platform.
Prospective data generation
Our relationship with NHS hospitals also allows us to access stored tissue samples from which DNA, RNA or protein can be extracted for new data generation. If the research need requires it, we are also able to prospectively collect these multi-omics data to enable, for example, the building up of patient biomarker data for markers that are not collected as part of routine clinical care.
Using our NGS Platform containing genetically enriched, phenotyped patient cohorts, we are able to curate disease specific, integrated multi-omics datasets. These deeply enriched datasets can then be applied to drug discovery and clinical development.